National Resilience, the fast-growing biomanufacturing company that has been quietly building a footprint around Cincinnati, has now made it official: the corporate headquarters is moving to Blue Ash, along with roughly $100 million in investment and about 200 new jobs. The shift from San Diego to the Tri‑State gives the Cincinnati suburbs another anchor tenant in a budding cluster of sterile injectable manufacturing and packaging operations in Butler County, a development regional boosters at REDI Cincinnati and JobsOhio have been chasing for years.
Resilience announced the relocation in a press release on Tuesday, noting that the new headquarters will sit at 10901 Kenwood Road. The Blue Ash site is set to anchor packaging, device assembly, and cold‑storage operations that support the company’s West Chester drug‑product plant, with the company expecting to add approximately 200 jobs in Blue Ash. The move is framed as part of a larger strategy to bolster U.S. sterile manufacturing capacity while knitting together Resilience’s Ohio operations, according to Resilience.
The Cincinnati Business Journal first detailed the scale of the project, reporting that Resilience plans to pour about $100 million into the Blue Ash headquarters and that corporate leadership has formally shifted from San Diego, in reporting by Chris Wetterich. As noted by The Business Journals, that nine‑figure price tag would represent a significant local capital commitment tied to the new campus.
Resilience’s Blue Ash move builds on earlier bets in the region. In January 2023, the company acquired AstraZeneca’s West Chester manufacturing site, a roughly 580,000‑square‑foot facility that handled filling and packaging work for the drugmaker, according to AstraZeneca. Together, the West Chester plant and the Blue Ash packaging campus effectively create a tightly integrated regional hub for sterile drug‑product work.
“We are happy to welcome Resilience to Ohio,” Gov. Mike DeWine said in the announcement, praising both the incoming jobs and the potential supply‑chain benefits. Blue Ash officials likewise welcomed their new corporate neighbor and promised support for workforce development as the headquarters ramps up. Resilience said it will schedule an official ribbon‑cutting and open house for press, community leaders, and other stakeholders at a later date, and the company also laid out plans to add additional injectable fill and finish capability at its West Chester site. Those comments and plans were included in the company’s release.
What This Means for Local Jobs and Training
State and regional partners, including JobsOhio and REDI Cincinnati, say they will help build a pipeline of technicians and packaging specialists to staff the expansions, with training programs tailored to cGMP roles and device‑assembly work. JobsOhio described the initiative as part of a wider strategy to attract skilled manufacturing jobs to Ohio and to prepare technicians for high‑quality positions at companies like Resilience, according to JobsOhio.
For Blue Ash, landing Resilience’s headquarters, combined with the West Chester manufacturing campus, strengthens the Cincinnati region’s claim as a national hub for sterile injectable manufacturing and could encourage more corporate investment in suburban office and industrial real estate. Company leaders say hiring and campus build‑out will roll out in stages over the coming months as the new headquarters comes fully online.
